Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889765 | 0.89 | DRD4 (0.40) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL27889746 | 0.83 | DRD4 (0.39) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL28038611 | 0.81 | DRD4 (0.40) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL2360299 | 0.76 | HCRTR1 (0.44) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| Hydrochloric Acid SCHEMBL3048178 | 0.75 | HCRTR1 (0.43) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL27889785 | 0.74 | DRD4 (0.40) | DRD4DRD3GRM2CCR5 | |
| SCHEMBL2360037 | 0.71 | SRD5A1 (0.47) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL28038276 | 0.71 | DRD4 (0.38) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL2749344 | 0.70 | HPGD (0.56) | DRD4DRD3HCRTR1HCRTR2ERCC5 | |
| SCHEMBL27538076 | 0.69 | SLC18A3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142623-A | Methods and compositions for improving cognitive function | AGENEBIO INC | 2015-12-09 | — | — | CN | disclosed |
| CN-103476255-A | Methods and compositions for improving cognitive function | UNIV JOHNS HOPKINS | 2013-12-25 | — | — | CN | disclosed |
| CN-102905532-A | Methods and compositions for improving cognitive function | UNIV JOHNS HOPKINS | 2013-01-30 | — | — | CN | disclosed |