Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584685 | 0.94 | EPHX2 (0.54) | EPHX2HDAC3HPGDHTTFAAH | |
| SCHEMBL8895173 | 0.94 | EPHX2 (0.54) | EPHX2HDAC3HPGDHTTFAAH | |
| SCHEMBL8895162 | 0.94 | EPHX2 (0.54) | EPHX2HDAC3HPGDHTTFAAH | |
| SCHEMBL8805244 | 0.93 | EPHX2 (0.51) | EPHX2CYP2C19CYP1A2CYP2C9HDAC3 | |
| Hydrochloric Acid SCHEMBL13584812 | 0.92 | EPHX2 (0.52) | EPHX2HDAC3HPGDHTTFAAH | |
| Hydrochloric Acid SCHEMBL8896288 | 0.92 | EPHX2 (0.52) | EPHX2HDAC3HPGDHTTFAAH | |
| Hydrochloric Acid SCHEMBL8896452 | 0.92 | EPHX2 (0.52) | EPHX2HDAC3HPGDHTTFAAH | |
| Hydrochloric Acid SCHEMBL4485174 | 0.92 | EPHX2 (0.52) | EPHX2HDAC3HPGDHTTFAAH | |
| Hydrochloric Acid SCHEMBL4471284 | 0.92 | EPHX2 (0.52) | EPHX2HDAC3HPGDHTTFAAH | |
| Hydrochloric Acid SCHEMBL4473390 | 0.92 | EPHX2 (0.52) | EPHX2HDAC3HPGDHTTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102725264-A | Biguanide derivative, preparation method thereof, and pharmaceutical composition containing same as an active ingredient | HANALL BIOPHARMA CO LTD | 2012-10-10 | — | — | CN | claimed |
| CN-102725264-B | Biguanide derivative, preparation method thereof, and pharmaceutical composition containing same as an active ingredient | HANALL BIOPHARMA CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-102725264-A | Biguanide derivative, preparation method thereof, and pharmaceutical composition containing same as an active ingredient | HANALL BIOPHARMA CO LTD | 2012-10-10 | — | — | CN | disclosed |