Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 19/20 | 0.63 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | STK25 | O00506 | 1/20 | 0.54 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | GAK | O14976 | 1/20 | 0.54 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.54 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.54 |
| ▸ | STK17B | O94768 | 1/20 | 0.54 |
| ▸ | STK10 | O94804 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911178 | 0.97 | EGFR (0.59) | EGFRERBB2SRCKDR | |
| SCHEMBL27893941 | 0.95 | EGFR (0.65) | EGFRERBB2SRCKDR | |
| SCHEMBL27911107 | 0.94 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL27893964 | 0.92 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL27893965 | 0.91 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL14854916 | 0.91 | EGFR (0.77) | EGFRERBB2SRCKDRSTK25 | |
| SCHEMBL14854761 | 0.91 | EGFR (0.77) | EGFRERBB2SRCKDRSTK25 | |
| SCHEMBL14854762 | 0.91 | EGFR (0.77) | EGFRERBB2SRCKDRSTK25 | |
| SCHEMBL14854917 | 0.91 | EGFR (0.77) | EGFRERBB2SRCKDRSTK25 | |
| SCHEMBL27911104 | 0.91 | EGFR (0.65) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | claimed |
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | disclosed |