Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.78 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.78 |
| ▸ | PDE2A | O00408 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655944 | 0.88 | PTGER4 (1.00) | PTGER4PTGER2 | |
| SCHEMBL2353056 | 0.88 | PTGER4 (1.00) | PTGER4PTGER2 | |
| SCHEMBL4090963 | 0.87 | PTGER4 (0.98) | PTGER4PTGER2 | |
| SCHEMBL14299976 | 0.86 | PTGER4 (0.82) | PTGER4PTGER2PDE2AALDH1A1LMNA | |
| SCHEMBL4090960 | 0.86 | PTGER4 (0.82) | PTGER4PTGER2PDE2A | |
| SCHEMBL2353283 | 0.86 | PTGER4 (0.82) | PTGER4PTGER2PDE2AALDH1A1LMNA | |
| SCHEMBL2353326 | 0.84 | PTGER4 (1.00) | PTGER4PTGER2PDE2A | |
| SCHEMBL14299809 | 0.84 | PTGER4 (1.00) | PTGER4PTGER2PDE2A | |
| SCHEMBL2351635 | 0.81 | PTGER4 (1.00) | PTGER4PTGER2PDE2AALDH1A1 | |
| SCHEMBL14299923 | 0.81 | PTGER4 (1.00) | PTGER4PTGER2PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770159-A | Use of EP-4 receptor antagonists for the treatment of IL-23 mediated diseases | RAQUALIA PHARMA INC | 2012-11-07 | — | — | CN | claimed |
| CN-102770159-A | Use of EP-4 receptor antagonists for the treatment of IL-23 mediated diseases | RAQUALIA PHARMA INC | 2012-11-07 | — | — | CN | disclosed |