Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | NCK1 | P16333 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771905 | 0.98 | EGFR (0.60) | EGFRALDH1A1PIK3CDPIK3CAFGFR4 | |
| SCHEMBL29985188 | 0.98 | EGFR (0.60) | EGFRALDH1A1PIK3CDPIK3CAFGFR4 | |
| SCHEMBL15147835 | 0.85 | EGFR (0.55) | EGFRALDH1A1PIK3CDPIK3CAFGFR4 | |
| SCHEMBL3535171 | 0.83 | PIK3CA (0.61) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL1771615 | 0.82 | EGFR (0.60) | EGFRALDH1A1CYP1A2IMPDH2TDO2 | |
| SCHEMBL27941975 | 0.80 | EGFR (0.80) | EGFRALDH1A1PIK3CDPIK3CAFGFR4 | |
| SCHEMBL21499259 | 0.78 | EGFR (0.44) | EGFRALDH1A1PIK3CDPIK3CAFGFR4 | |
| SCHEMBL29804792 | 0.78 | PIK3CA (0.51) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL8644295 | 0.77 | PIK3CA (0.73) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL29804751 | 0.77 | PIK3CA (0.54) | EGFRPIK3CDPIK3CAFGFR4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746280-A | Pyrimidone compound and preparation method thereof | CHENGDU WANDONG PAHRMACEUTICAL CO LTD | 2012-10-24 | — | — | CN | disclosed |