Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676884 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL537020 | 0.91 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2674468 | 0.89 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2674752 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2676038 | 0.87 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2872776 | 0.87 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL537076 | 0.86 | KCNH2 (0.39) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL2878364 | 0.85 | TOP1 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL2677104 | 0.85 | TOP1 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL537467 | 0.85 | KCNH2 (0.41) | KDM4EALDH1A1HPGDHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115184-A2 | HYDROXYTHIENOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | WO | claimed |