Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902067 | 0.87 | TACR1 (0.33) | TACR1TACR2BACE1 | |
| SCHEMBL27901998 | 0.86 | TACR1 (0.42) | TACR1TACR2BACE1 | |
| SCHEMBL5624144 | 0.83 | — | — | |
| SCHEMBL27901982 | 0.82 | TACR1 (0.43) | TACR1BACE1 | |
| SCHEMBL5624134 | 0.79 | BCHE (0.32) | TACR1TACR2 | |
| SCHEMBL5626484 | 0.77 | TACR1 (0.40) | TACR1BACE1 | |
| SCHEMBL27919744 | 0.77 | TACR1 (0.32) | TACR1TACR2BACE1 | |
| SCHEMBL27919745 | 0.77 | CETP (0.39) | TACR1 | |
| SCHEMBL27902000 | 0.76 | TACR1 (0.32) | TACR1TACR2BACE1 | |
| SCHEMBL27902051 | 0.76 | BACE1 (0.32) | TACR1TACR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102303-A | Benzylamine derivatives as CETP inhibitors | REDDY US THERAPEUTICS INC | 2013-05-15 | — | — | CN | disclosed |