SCHEMBL28802451

SCHEMBL28802451

CCCC(Cl)Cl.N#CCCCCC#N

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL906778 0.79 TSHR (0.39) TSHRALDH1A1TDP1CYP3A4MAPT
SCHEMBL27906075 0.78
SCHEMBL21799 0.78
SCHEMBL10692856 0.76 TSHR (0.56) TSHRALDH1A1TDP1CYP3A4MAPT
Water SCHEMBL27972168 0.75
SCHEMBL28205094 0.75 TSHR (0.53) TSHRALDH1A1TDP1CYP3A4MAPT
SCHEMBL27494430 0.75 TSHR (0.81) TSHRALDH1A1TDP1CYP3A4MAPT
SCHEMBL21555 0.75
SCHEMBL365120 0.75
SCHEMBL11086025 0.75 TSHR (0.55) TSHRALDH1A1TDP1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102153459-B Method for preparing 5-chloro-valeryl chloride and adipoyl chloride simultaneously by one-pot method GENCHEM CHANGZHOU CO LTD 2013-04-24 CN claimed
CN-102153459-B Method for preparing 5-chloro-valeryl chloride and adipoyl chloride simultaneously by one-pot method GENCHEM CHANGZHOU CO LTD 2013-04-24 CN disclosed