Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19641703 | 0.88 | BRD4 (0.39) | BRD4SMYD3SYKNPC1RAB9A | |
| SCHEMBL28802499 | 0.82 | BRD4 (0.62) | BRD4NPC1RAB9A | |
| SCHEMBL19641880 | 0.81 | BRD4 (0.49) | BRD4NPC1RAB9A | |
| SCHEMBL28802495 | 0.80 | SYK (0.36) | SMYD3SYKNPC1RAB9APOLB | |
| SCHEMBL28802480 | 0.80 | BRD4 (0.62) | BRD4NPC1RAB9A | |
| SCHEMBL19642320 | 0.79 | BRD4 (0.45) | BRD4SMYD3NPC1RAB9A | |
| SCHEMBL29831147 | 0.79 | BRD4 (0.45) | BRD4SMYD3NPC1RAB9A | |
| SCHEMBL28802468 | 0.79 | BRD4 (0.61) | BRD4NPC1RAB9A | |
| SCHEMBL19641713 | 0.79 | BRD4 (0.47) | BRD4NPC1RAB9ADPP4DPP9 | |
| SCHEMBL19641665 | 0.79 | BRD4 (0.49) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153646-B | Pyridine dicarboxamide derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2022-08-02 | — | — | CN | disclosed |