Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784895 | 0.90 | F10 (0.43) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL784539 | 0.87 | TLR9 (0.43) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL784885 | 0.83 | TLR9 (0.42) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL785591 | 0.83 | F10 (0.44) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL785813 | 0.82 | TLR9 (0.41) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL785172 | 0.82 | F10 (0.41) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL784991 | 0.81 | F10 (0.46) | F10TLR9TLR8TLR7F2 | |
| SCHEMBL785281 | 0.81 | POLB (0.41) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL784416 | 0.81 | TLR9 (0.40) | F10TLR9TLR8TLR7CNR2 | |
| SCHEMBL785542 | 0.81 | HPGD (0.44) | F10TLR9TLR8TLR7ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | claimed |
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |