SCHEMBL2880260

SCHEMBL2880260

Clc1ccc(-c2cnc[nH]2)c(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 16/20 0.54
CYP3A4 P08684 1/20 0.42
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ASIC3 Q9UHC3 1/20 0.40
ADRA2A P08913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL871858 0.74 IDO1 (0.71) IDO1CYP3A4ADRA2A
SCHEMBL1948551 0.72 IDO1 (0.77) IDO1CYP3A4ADRA2A
SCHEMBL12676462 0.72 IDO1 (0.62) IDO1CYP3A4POLBSMN1; SMN2ADRA2A
SCHEMBL26259980 0.71 IDO1 (0.64) IDO1CYP3A4ADRA2A
SCHEMBL28131195 0.70 IDO1 (0.47) IDO1POLBASIC3
SCHEMBL12676754 0.70 IDO1 (1.00) IDO1CYP3A4ADRA2A
SCHEMBL31190899 0.69 IDO1 (0.54) IDO1CYP3A4ADRA2A
SCHEMBL29859756 0.69 MRGPRX4 (0.49) IDO1
SCHEMBL30564601 0.69 IDO1 (0.53) IDO1CYP3A4POLBSMN1; SMN2ASIC3
SCHEMBL7194641 0.68 IDO1 (0.59) IDO1CYP3A4POLBSMN1; SMN2ASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102119240-B Surface treating agent for copper or copper alloy and use thereof SHIKOKU CHEM 2014-07-30 CN disclosed
CN-102119240-A Surface treating agent for copper or copper alloy and use thereof SHIKOKU CHEM 2011-07-06 CN disclosed
WO-2010016620-A1 SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2010-02-11 WO disclosed