Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808979 | 0.93 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL24732581 | 0.93 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL29809182 | 0.93 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL24732764 | 0.93 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL29809061 | 0.88 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL24732580 | 0.88 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL28802653 | 0.88 | CYP2D6 (0.45) | CYP2D6CYP2C9HIF1A | |
| SCHEMBL24732841 | 0.85 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL24732748 | 0.82 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL29809441 | 0.82 | TLR7 (0.51) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |