Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391199 | 1.00 | POLB (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL28459037 | 1.00 | POLB (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL5391201 | 1.00 | POLB (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL9207674 | 1.00 | POLB (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL8579324 | 1.00 | POLB (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL8579326 | 1.00 | POLB (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL9728361 | 0.91 | TDP1 (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL6778186 | 0.91 | TDP1 (0.48) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL9203713 | 0.90 | POLB (0.45) | POLBTDP1ATMALDH1A1MAPT | |
| SCHEMBL9207538 | 0.90 | POLB (0.45) | POLBTDP1ATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805162-B | Continuous production method and device for meropenem side chain key intermediate O powder | 湖北华洲药业有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-114773248-B | Continuous production method and device for meropenem side chain | 湖北华洲药业有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114805162-A | Continuous production method and device for meropenem side chain key intermediate O powder | 湖北华洲药业有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114773248-A | Continuous production method and device for meropenem side chain | 湖北华洲药业有限公司 | 2022-07-22 | — | — | CN | disclosed |