SCHEMBL2880321

SCHEMBL2880321

CCCCC(Cl)(Cl)c1ccc2ccccc2c1C(Cl)(Cl)CCCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNJ11 Q14654 3/20 0.37
ABCC9 O60706 2/20 0.37
ABCC8 Q09428 2/20 0.37
KCNJ8 Q15842 2/20 0.37
GAA P10253 5/20 0.35
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 4/20 0.35
NPC1 O15118 4/20 0.35
HTT P42858 4/20 0.35
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GLA P06280 1/20 0.35
RCE1 Q9Y256 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2880467 0.95 GAA (0.38) KCNJ11ABCC9ABCC8KCNJ8GAA
SCHEMBL2875925 0.94 GAA (0.39) KCNJ11ABCC9ABCC8KCNJ8GAA
SCHEMBL2877903 0.94 GAA (0.39) KCNJ11ABCC9ABCC8KCNJ8GAA
SCHEMBL2873415 0.90 KCNJ11 (0.39) KCNJ11ABCC9ABCC8KCNJ8ALDH1A1
SCHEMBL6680295 0.82 HTR1B (0.38) GAAALDH1A1KDM4ENPC1HTT
SCHEMBL2875180 0.80 CYP2A6 (0.38) KCNJ11ABCC9ABCC8KCNJ8GAA
SCHEMBL6681462 0.78 KDM4E (0.37) GAAALDH1A1KDM4ENPC1HTT
SCHEMBL2880487 0.76 GAA (0.36) KCNJ11ABCC9ABCC8KCNJ8GAA
SCHEMBL6682626 0.76 KDM4E (0.38) GAAALDH1A1KDM4ENPC1HTT
SCHEMBL6686907 0.76 KDM4E (0.38) GAAALDH1A1KDM4ENPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed