Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.56 |
| ▸ | BTK | Q06187 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486599 | 0.94 | JAK3 (0.58) | JAK3BTKAURKAPDPK1AURKB | |
| SCHEMBL12486601 | 0.94 | JAK3 (0.58) | JAK3BTKAURKAPDPK1AURKB | |
| SCHEMBL12484351 | 0.89 | BTK (0.51) | JAK3BTKAURKAPDPK1AURKB | |
| SCHEMBL12484356 | 0.89 | BTK (0.51) | JAK3BTKAURKAPDPK1AURKB | |
| SCHEMBL12484536 | 0.87 | HRH4 (0.49) | JAK3BTKHRH4SYK | |
| SCHEMBL12485681 | 0.87 | HRH4 (0.49) | JAK3BTKHRH4 | |
| SCHEMBL12484534 | 0.87 | HRH4 (0.49) | JAK3BTKHRH4SYK | |
| SCHEMBL24851725 | 0.81 | BTK (0.57) | JAK3BTKAURKAPDPK1AURKB | |
| SCHEMBL12486446 | 0.81 | PDCD1LG2 (0.43) | JAK3BTKHRH4SYK | |
| SCHEMBL12485004 | 0.81 | HRH4 (0.56) | HRH4SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103391935-A | Diaminopyrimidine derivatives and process for preparing same | YUHAN CORP | 2013-11-13 | — | — | CN | disclosed |