Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845821 | 0.86 | MAPT (0.46) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL30892666 | 0.86 | CYP1B1 (0.50) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL27549569 | 0.85 | MAPT (0.45) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL10425121 | 0.82 | MAPT (0.47) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL6500195 | 0.82 | MAPT (0.42) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL1470132 | 0.81 | RECQL (0.45) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL9439999 | 0.81 | MAPT (0.46) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL27923700 | 0.80 | MAPT (0.43) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL27998786 | 0.80 | MAPT (0.40) | MAPTCYP1B1MAOBBCHEPLIN1 | |
| SCHEMBL27790759 | 0.80 | MAPT (0.45) | MAPTCYP1B1MAOBBCHEPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103342653-B | Preparation method and application of chalcone amide derivatives | XINJIANG TECH INST PHYSICS CAS | 2015-04-01 | — | — | CN | disclosed |
| CN-103342653-A | Preparation method and application of chalcone amide derivatives | XINJIANG TECH INST PHYSICS CAS | 2013-10-09 | — | — | CN | disclosed |