Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926193 | 0.97 | GSK3B (0.39) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL9952339 | 0.90 | DDB1 (0.44) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL9952422 | 0.89 | GSK3B (0.51) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL9952674 | 0.87 | DDB1 (0.42) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL10194961 | 0.86 | GSK3B (0.46) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL10195389 | 0.86 | GSK3B (0.49) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| Tert-Butyl Formate SCHEMBL28806326 | 0.85 | GSK3B (0.45) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| Hydrochloric Acid SCHEMBL15312398 | 0.85 | GSK3B (0.48) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL15312572 | 0.84 | GSK3B (0.40) | GSK3BDYRK1ACLK2CLK3FGFR1 | |
| SCHEMBL10195391 | 0.83 | GSK3B (0.46) | GSK3BDYRK1ACLK2CLK3FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429585-A | Indazolyl triazole derivatives as interleukin-1 receptor associated kinase inhibitors | MERCK SERONO SA | 2013-12-04 | — | — | CN | disclosed |