Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.68 |
| ▸ | YES1 | P07947 | 4/20 | 0.68 |
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.49 |
| ▸ | CIT | O14578 | 1/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272391 | 0.90 | SRC (0.83) | SRCPDGFRBYES1ABL1KDR | |
| SCHEMBL4273035 | 0.85 | SRC (0.81) | SRCPDGFRB | |
| SCHEMBL4267606 | 0.84 | SRC (0.81) | SRCPDGFRBYES1ABL1 | |
| SCHEMBL4278298 | 0.83 | SRC (0.81) | SRCPDGFRBYES1ABL1KDR | |
| SCHEMBL15095264 | 0.82 | SRC (0.84) | SRCPDGFRBYES1ABL1KDR | |
| SCHEMBL4273719 | 0.81 | SRC (1.00) | SRCPDGFRBYES1ABL1KDR | |
| SCHEMBL4272211 | 0.80 | SRC (0.83) | SRCPDGFRBYES1ABL1KDR | |
| SCHEMBL4269658 | 0.78 | SRC (1.00) | SRCPDGFRBYES1ABL1KDR | |
| Water SCHEMBL4268454 | 0.75 | SRC (0.92) | SRCPDGFRBYES1ABL1KDR | |
| SCHEMBL4273587 | 0.75 | SRC (0.81) | SRCPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101426772-B | Benzotriazine inhibitors of kinases | TARGEGEN INC | 2014-01-08 | — | — | CN | disclosed |