⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13556461 | 0.77 | — | — | |
| SCHEMBL23829569 | 0.71 | — | — | |
| SCHEMBL28044603 | 0.71 | — | — | |
| SCHEMBL13556464 | 0.71 | — | — | |
| SCHEMBL4200 | 0.69 | — | — | |
| SCHEMBL9418842 | 0.69 | — | — | |
| SCHEMBL1331044 | 0.69 | — | — | |
| SCHEMBL11341198 | 0.67 | — | — | |
| SCHEMBL15344654 | 0.67 | TSHR (0.42) | — | |
| SCHEMBL15344653 | 0.67 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698984-A | Novel bicyclic compounds for use as medicaments, in particular for the treatment of parkinson's disease | H·科斯特 | 2018-10-23 | — | — | CN | claimed |
| CN-103059088-A | Dammarane saponin derivatives with novel structure as well as preparation method and anti-microbial application thereof | UNIV YANTAI | 2013-04-24 | — | — | CN | claimed |
| CN-102924556-A | (20S, 24R)-ocotillol type ginsenoside derivative having antibacterial activity and preparation method and application thereof | UNIV YANTAI | 2013-02-13 | — | — | CN | claimed |
| CN-102875628-A | (20S,24S)-ocotillol ginsenoside derivatives with antibacterial activity, and preparation method and application thereof | UNIV CHINA PHARMA | 2013-01-16 | — | — | CN | claimed |
| EP-0596197-B1 | Lubricating composition comprising an N-acyl-N-hydrocarbon- oxyalkyl aspartic acid compound | KING INDUSTRIES INC (US) | 1997-01-29 | — | — | EP | claimed |
| CN-110167926-A | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | 米托布里奇公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-107586271-B | 4-(N- maleimidoethyl) amido -4- oxo-butynic acid preparation, structure and purposes | 齐鲁工业大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-110079525-A | Antisense nucleic acid | 日本新药株式会社 | 2019-08-02 | — | — | CN | disclosed |
| CN-110055244-A | Antisense nucleic acid | 日本新药株式会社 | 2019-07-26 | — | — | CN | disclosed |
| CN-110055243-A | Antisense nucleic acid | 日本新药株式会社 | 2019-07-26 | — | — | CN | disclosed |
| CN-108698984-A | Novel bicyclic compounds for use as medicaments, in particular for the treatment of parkinson's disease | H·科斯特 | 2018-10-23 | — | — | CN | disclosed |
| CN-108588073-A | antisense nucleic acid | 日本新药株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-102924556-A | (20S, 24R)-ocotillol type ginsenoside derivative having antibacterial activity and preparation method and application thereof | UNIV YANTAI | 2013-02-13 | — | — | CN | disclosed |
| CN-102875628-A | (20S,24S)-ocotillol ginsenoside derivatives with antibacterial activity, and preparation method and application thereof | UNIV CHINA PHARMA | 2013-01-16 | — | — | CN | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| EP-1633340-B1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORP (US) | 2010-11-10 | — | — | EP | disclosed |
| US-20040082578-A1 | Arylindenopyridines and related therapeutic and prophylactic methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-04-29 | — | — | US | disclosed |
| CN-1082370-C | Pharmaceutical composition containing 4-oxo-butyric acid | MERCK PATENT GMBH (DE) | 2002-04-10 | — | — | CN | disclosed |
| US-6143787-A | HETEROCYCLIC OR AROMATIC OXOACIDS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2000-11-07 | — | — | US | disclosed |
| CN-1227538-A | Pharmaceutical composition containing 4-oxo-butynic acid | MERCK PATENT GMBH (DE) | 1999-09-01 | — | — | CN | disclosed |