Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936057 | 0.88 | PPARG (0.37) | PPARGPPARAPPARDPTGES2 | |
| SCHEMBL28806426 | 0.87 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL27909994 | 0.86 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL27936024 | 0.85 | PPARG (0.39) | PPARGPPARAPPARD | |
| SCHEMBL27950252 | 0.85 | PPARG (0.38) | PPARGPPARAPPARD | |
| SCHEMBL27936046 | 0.83 | PPARG (0.37) | PPARGPPARAPPARDMAOAMAOB | |
| SCHEMBL27950238 | 0.83 | POLB (0.44) | PPARGPPARAPPARDMAOAMAOB | |
| SCHEMBL28809330 | 0.83 | PPARG (0.37) | PPARGPPARAPPARDMAOAMAOB | |
| SCHEMBL27936050 | 0.83 | PPARG (0.37) | PPARGPPARAPPARD | |
| SCHEMBL27936030 | 0.83 | PPARG (0.37) | PPARGPPARAPPARDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | disclosed |