Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503277 | 0.91 | EGLN1 (0.77) | EGLN1 | |
| SCHEMBL12503281 | 0.91 | EGLN1 (0.77) | EGLN1 | |
| SCHEMBL28964305 | 0.86 | EGLN1 (0.84) | EGLN1 | |
| SCHEMBL27951478 | 0.85 | EGLN1 (0.74) | EGLN1 | |
| SCHEMBL28807628 | 0.84 | EGLN1 (0.83) | EGLN1 | |
| SCHEMBL12502566 | 0.83 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL12502373 | 0.82 | EGLN1 (0.71) | EGLN1 | |
| SCHEMBL28809535 | 0.81 | EGLN1 (0.84) | EGLN1 | |
| SCHEMBL27951502 | 0.81 | EGLN1 (0.90) | EGLN1 | |
| SCHEMBL28947546 | 0.81 | EGLN1 (0.88) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608346-A | Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase | FIBROGEN INC | 2014-02-26 | — | — | CN | disclosed |