Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808693 | 0.82 | CYP3A4 (0.51) | IDO1MAOBMMP2MMP9MMP12 | |
| SCHEMBL28808708 | 0.80 | PARP10 (0.45) | IDO1L3MBTL1 | |
| SCHEMBL7656159 | 0.76 | IDO1 (0.59) | IDO1MAOBPOLBMMP2MMP9 | |
| SCHEMBL13416556 | 0.75 | IDO1 (0.58) | IDO1MAOBPOLBMMP2MMP9 | |
| SCHEMBL28808706 | 0.72 | IDO1 (0.49) | IDO1MAOBPOLBPARP1 | |
| SCHEMBL28947455 | 0.72 | MAOB (0.44) | MAOBTAAR1THRATHRBCTBP2 | |
| SCHEMBL3763603 | 0.72 | IDO1 (0.58) | IDO1MAOBPOLBMMP2MMP9 | |
| SCHEMBL28808716 | 0.71 | IDO1 (0.46) | IDO1MAOBMAOAL3MBTL1 | |
| SCHEMBL28808704 | 0.71 | NR4A2 (0.46) | L3MBTL1 | |
| SCHEMBL10773353 | 0.70 | IDO1 (0.56) | IDO1MAOBMMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079747-B | N-benzyloxy substituted symmetrical oxamide compound and preparation method and application thereof | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |