SCHEMBL28809152

SCHEMBL28809152

O=C(O)c1cc(C(=O)O)cc(S(=O)(=O)O)c1.O=C(OCCO)c1cccc(C(=O)OCCO)c1.[NaH]

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.54
FYN P06241 1/20 0.54
SLC7A5 Q01650 1/20 0.48
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 3/20 0.44
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.40
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 1/20 0.39
IL1RN P18510 1/20 0.39
APEX1 P27695 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27912595 0.90 LCK (0.62) LCKFYNSLC7A5CA1CA2
SCHEMBL9161519 0.89 CA1 (0.52) SLC7A5CA1CA2CYP2C19TDP1
SCHEMBL8782111 0.87 CA1 (0.53) SLC7A5CA1CA2CYP2C19TDP1
SCHEMBL1602982 0.85 LCK (0.48) LCKFYNSLC7A5CA1CA2
SCHEMBL28345285 0.85 SLC7A5 (0.57) SLC7A5CA1CA2TDP1ALDH1A1
SCHEMBL3292533 0.84 SLC7A5 (0.58) SLC7A5CA1CA2TDP1ALDH1A1
SCHEMBL31148945 0.84 LCK (0.50) LCKFYNSLC7A5CA1CA2
SCHEMBL3846745 0.84 LCK (0.50) LCKFYNSLC7A5CA1CA2
SCHEMBL31148946 0.84 LCK (0.50) LCKFYNSLC7A5CA1CA2
SCHEMBL29540241 0.84 SLC7A5 (0.58) SLC7A5CA1CA2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552499-B Block polyester polyol, preparation method thereof and waterborne polyurethane 万华化学集团股份有限公司 2022-07-12 CN claimed