Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809289 | 0.89 | PARP1 (1.00) | PARP1 | |
| SCHEMBL28810281 | 0.89 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3092602 | 0.89 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3083868 | 0.82 | PARP1 (0.73) | PARP1 | |
| SCHEMBL3094418 | 0.81 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3103147 | 0.80 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3094511 | 0.78 | PARP1 (0.77) | PARP1 | |
| SCHEMBL3096257 | 0.77 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3096796 | 0.77 | PARP1 (0.82) | PARP1 | |
| SCHEMBL871829 | 0.76 | PARP1 (1.00) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929674-B | Compound containing 1, 4-dihydro quinazoline structure, preparation method and application thereof | 中国药科大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-113929674-A | Compound containing 1, 4-dihydroquinazoline structure and preparation method and application thereof | 中国药科大学 | 2022-01-14 | — | — | CN | disclosed |