Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29753935 | 1.00 | IKBKE (0.50) | IKBKETBK1DYRK1ACLK2CLK3 | |
| SCHEMBL29753996 | 0.85 | DYRK1A (0.48) | DYRK1ACLK2CLK3ROCK1ROCK2 | |
| SCHEMBL28810265 | 0.85 | DYRK1A (0.48) | DYRK1ACLK2CLK3ROCK1ROCK2 | |
| SCHEMBL29754130 | 0.83 | DHODH (0.54) | DYRK1ANR4A2MAPT | |
| SCHEMBL28947575 | 0.83 | DHODH (0.54) | DYRK1ANR4A2MAPT | |
| SCHEMBL23533877 | 0.81 | DYRK1A (0.70) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL29753923 | 0.81 | DYRK1A (0.70) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL28811003 | 0.79 | DYRK1A (0.51) | DYRK1ACLK2CLK3KMT2AALDH1A1 | |
| SCHEMBL29754069 | 0.79 | BACE1 (0.60) | DYRK1AKMT2AALDH1A1MAPTBACE1 | |
| SCHEMBL28811002 | 0.79 | DYRK1A (0.51) | DYRK1ACLK2CLK3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |