Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30161850 | 1.00 | PDE4B (0.47) | PDE4BBCHETDP1HTTATM | |
| SCHEMBL2348371 | 0.94 | BCHE (0.44) | PDE4BBCHETDP1HTTATM | |
| SCHEMBL30161883 | 0.94 | PDE4B (0.48) | PDE4BBCHETDP1HTTATM | |
| SCHEMBL2348366 | 0.94 | BCHE (0.44) | PDE4BBCHETDP1HTTATM | |
| SCHEMBL28809883 | 0.94 | PDE4B (0.48) | PDE4BBCHETDP1HTTATM | |
| SCHEMBL31200717 | 0.91 | PDE4B (0.50) | PDE4BHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20549043 | 0.87 | BCHE (0.45) | PDE4BBCHETDP1ATMNT5E | |
| SCHEMBL19063875 | 0.87 | BCHE (0.45) | PDE4BBCHETDP1ATMNT5E | |
| SCHEMBL19063874 | 0.87 | BCHE (0.45) | PDE4BBCHETDP1ATMNT5E | |
| SCHEMBL28528480 | 0.84 | PDE4B (0.52) | PDE4BHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867717-A | Heteroaryl dihydropyrimidine derivatives and methods for treating hepatitis b infection | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |