Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511790 | 0.84 | HRH3 (0.35) | HRH4HRH3ABL1BCRKIT | |
| SCHEMBL511704 | 0.81 | MAOB (0.36) | HRH4HRH3ABL1BCR | |
| SCHEMBL18559791 | 0.80 | CYP3A4 (0.33) | HRH4HRH3PTPN11KIT | |
| SCHEMBL27942853 | 0.80 | ABL1 (0.41) | HRH4HRH3ABL1BCR | |
| SCHEMBL512835 | 0.80 | HRH3 (0.34) | HRH4HRH3 | |
| SCHEMBL18559820 | 0.78 | HRH3 (0.41) | HRH4HRH3ABL1BCR | |
| SCHEMBL513595 | 0.77 | SMN1; SMN2 (0.43) | HRH4HRH3 | |
| SCHEMBL511681 | 0.76 | HRH3 (0.32) | HRH4HRH3 | |
| SCHEMBL512628 | 0.76 | CYP3A4 (0.34) | HRH4HRH3 | |
| SCHEMBL1225782 | 0.75 | ABL1 (0.43) | HRH4HRH3ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103328451-A | Compounds for the reduction of beta-amyloid production | BRISTOL MYERS SQUIBB CO | 2013-09-25 | — | — | CN | disclosed |