Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.71 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672524 | 0.86 | PTGDR2 (0.65) | HDAC6HDAC1CYP2C9PTGDR2HDAC10 | |
| SCHEMBL1080466 | 0.83 | HDAC6 (1.00) | HDAC6HDAC1ENPP2HDAC10HDAC8 | |
| SCHEMBL28810829 | 0.80 | HDAC6 (0.68) | HDAC6HDAC1ENPP2PTGDR2HDAC10 | |
| SCHEMBL28665679 | 0.79 | PTGDR2 (0.55) | HDAC6HDAC1CYP2C9PTGDR2HDAC10 | |
| SCHEMBL1056164 | 0.79 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL14489612 | 0.79 | F10 (0.73) | HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL28666328 | 0.78 | HDAC6 (0.80) | HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL28688093 | 0.77 | PTGDR2 (0.54) | CYP2C9PTGDR2 | |
| SCHEMBL28683406 | 0.77 | CYP2C9 (0.65) | HDAC6HDAC1CYP2C9PTGDR2HDAC10 | |
| SCHEMBL12805487 | 0.77 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591323-A | Hydroxamic acid histone deacetylase inhibitor containing tetrahydrocarboline structure and preparation method and application thereof | 济南大学 | 2022-06-07 | — | — | CN | disclosed |