Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23301153 | 1.00 | DDB1 (0.50) | DDB1CRBNS1PR1HDAC8CNR1 | |
| SCHEMBL23301296 | 0.96 | DDB1 (0.47) | DDB1CRBNS1PR1HDAC8CNR1 | |
| SCHEMBL28810174 | 0.94 | DDB1 (0.48) | DDB1CRBNS1PR1HDAC8 | |
| SCHEMBL23302130 | 0.94 | DDB1 (0.48) | DDB1CRBNS1PR1HDAC8 | |
| Hydrochloric Acid SCHEMBL23301513 | 0.90 | DDB1 (0.45) | DDB1CRBNS1PR1HDAC8 | |
| SCHEMBL25168320 | 0.90 | DDB1 (0.52) | DDB1CRBNHDAC8 | |
| SCHEMBL25173024 | 0.90 | DDB1 (0.52) | DDB1CRBNHDAC8 | |
| SCHEMBL23301396 | 0.90 | DDB1 (0.52) | DDB1CRBNHDAC8 | |
| SCHEMBL24207119 | 0.86 | CRBN (0.51) | DDB1CRBNS1PR1HDAC8SLC18A3 | |
| SCHEMBL23301372 | 0.86 | S1PR1 (0.54) | DDB1CRBNS1PR1DRD2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728936-A | Bifunctional compounds for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2022-07-08 | — | — | CN | disclosed |