Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421491 | 0.88 | NTRK1 (0.48) | NTRK1 | |
| SCHEMBL12984876 | 0.82 | NTRK1 (0.60) | NTRK1 | |
| SCHEMBL27934669 | 0.80 | NTRK1 (0.62) | NTRK1 | |
| SCHEMBL12985126 | 0.75 | NTRK1 (0.49) | NTRK1 | |
| SCHEMBL13041959 | 0.74 | NTRK1 (0.37) | NTRK1 | |
| SCHEMBL27975444 | 0.73 | LRRK2 (0.42) | NTRK1 | |
| SCHEMBL16091256 | 0.73 | NTRK1 (0.36) | NTRK1 | |
| SCHEMBL13616224 | 0.73 | BRD4 (0.42) | NTRK1 | |
| SCHEMBL12985514 | 0.73 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL27949599 | 0.72 | NTRK1 (0.47) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103534257-A | Pyrrolo [2, 3 -d] pyrimidine derivatives as inhibitors of tropomyosin- related kinases | PFIZER | 2014-01-22 | — | — | CN | disclosed |