Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | OGT | O15294 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20555901 | 0.84 | ESR1 (0.46) | RAB9ATSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL28452996 | 0.80 | GAA (0.46) | KMT2ARAB9ATSHRALDH1A1LMNA | |
| SCHEMBL28458116 | 0.75 | ESR1 (0.50) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL16961866 | 0.71 | MEN1 (0.44) | KMT2AMEN1RAB9ATSHRALDH1A1 | |
| SCHEMBL16961840 | 0.71 | MEN1 (0.44) | KMT2AMEN1RAB9ATSHRALDH1A1 | |
| SCHEMBL16961864 | 0.70 | MEN1 (0.43) | KMT2AMEN1RAB9ATSHRALDH1A1 | |
| SCHEMBL16962168 | 0.68 | KMT2A (0.44) | KMT2AMEN1RAB9ATSHRALDH1A1 | |
| SCHEMBL16952601 | 0.68 | MEN1 (0.41) | KMT2AMEN1RAB9ATSHRALDH1A1 | |
| SCHEMBL16961842 | 0.68 | MEN1 (0.41) | KMT2AMEN1RAB9ATSHRALDH1A1 | |
| SCHEMBL16962166 | 0.67 | MEN1 (0.43) | KMT2AMEN1RAB9ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291065-B | Novel isoindoline derivative, pharmaceutical composition and application thereof | 康朴生物医药技术（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |