Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.80 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.80 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353056 | 0.89 | PTGER4 (1.00) | PTGER4PTGER2 | |
| SCHEMBL13655944 | 0.89 | PTGER4 (1.00) | PTGER4PTGER2 | |
| SCHEMBL4090963 | 0.88 | PTGER4 (0.98) | PTGER4PTGER2 | |
| Benzoic Acid SCHEMBL27959675 | 0.86 | PTGER4 (0.74) | PTGER4PTGER2SRD5A2 | |
| SCHEMBL16524288 | 0.82 | PTGER4 (0.69) | PTGER4PTGER2SRD5A2PPARA | |
| SCHEMBL27877468 | 0.80 | PTGER4 (0.79) | PTGER4PTGER2 | |
| SCHEMBL2353281 | 0.80 | PTGER4 (0.79) | PTGER4PTGER2 | |
| SCHEMBL4091100 | 0.80 | PTGER4 (0.64) | PTGER4PTGER2SRD5A2NPC1PPARG | |
| SCHEMBL4090960 | 0.79 | PTGER4 (0.82) | PTGER4PTGER2 | |
| SCHEMBL14299976 | 0.79 | PTGER4 (0.82) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541778-B | Thiophenecarboxamide derivatives as EP4 receptor ligands | MERCK FROSST CANADA LTD. (CA) | 2014-10-08 | — | — | CN | disclosed |