Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749966 | 0.92 | BRD4 (0.53) | BRD4KDM4EL3MBTL1ALOX15TSHR | |
| SCHEMBL21750007 | 0.83 | BRD4 (0.53) | BRD4KDM4EL3MBTL1ALOX15TSHR | |
| SCHEMBL24437385 | 0.80 | HPGD (0.44) | BRD4KDM4EL3MBTL1ALOX15TSHR | |
| SCHEMBL21830986 | 0.79 | BRD4 (0.79) | BRD4KDM4EL3MBTL1ALOX15TSHR | |
| SCHEMBL29922633 | 0.79 | BRD4 (0.79) | BRD4KDM4EL3MBTL1ALOX15TSHR | |
| SCHEMBL21750022 | 0.79 | BRD4 (0.52) | BRD4ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1465393 | 0.79 | BRD4 (0.47) | BRD4KDM4EL3MBTL1ALOX15TSHR | |
| SCHEMBL767485 | 0.77 | TSHR (0.48) | KDM4EL3MBTL1ALOX15TSHRALDH1A1 | |
| SCHEMBL518596 | 0.77 | BRD4 (0.46) | BRD4KDM4EL3MBTL1ALOX15ALDH1A1 | |
| SCHEMBL21749970 | 0.76 | MAPT (0.44) | BRD4KDM4EL3MBTL1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291065-B | Novel isoindoline derivative, pharmaceutical composition and application thereof | 康朴生物医药技术（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |