Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328489 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL8329901 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL8330227 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL522714 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL9715621 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL523889 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL522715 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL523888 | 1.00 | KMT2A (0.81) | KMT2AMAPK1MAPTLMNAALOX15 | |
| SCHEMBL1263214 | 0.90 | KMT2A (1.00) | KMT2AMAPK1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL739575 | 0.90 | KMT2A (1.00) | KMT2AMAPK1MAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827090-B | Substituted quinolines and their use as pharmaceuticals | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |
| CN-103827090-A | Substituted quinolines and their use as pharmaceuticals | BOEHRINGER INGELHEIM INT | 2014-05-28 | — | — | CN | disclosed |