Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811202 | 0.87 | MAPT (0.49) | MAPTPOLBALDH1A1RAB9AMAPK1 | |
| SCHEMBL28811737 | 0.87 | MAPT (0.48) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28811233 | 0.82 | TSHR (0.49) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28811683 | 0.81 | MAPT (0.63) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28811205 | 0.77 | MAPT (0.44) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28811734 | 0.75 | TDP1 (0.47) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL26188701 | 0.73 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL4960436 | 0.73 | MAPT (0.53) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL23747775 | 0.72 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3955088 | 0.72 | MAPT (0.62) | MAPTPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874109-A | Novel alpha-cyano-beta-amino acrylate compound and synthetic method thereof | 福建师范大学 | 2022-08-09 | — | — | CN | disclosed |