Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968890 | 0.85 | KDR (0.40) | KDRMAPK9MAPK10ALDH1A1POLB | |
| SCHEMBL27969018 | 0.81 | MAPK9 (0.43) | KDRMAPK9MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL26562756 | 0.81 | KDR (0.55) | KDRMAPK9MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL27969021 | 0.78 | KDR (0.40) | KDRMAPK9MAPK10ALDH1A1MAPKAPK2 | |
| SCHEMBL2874163 | 0.76 | HDAC4 (0.40) | KDM4ENPC1PKMRAB9AKMT2A | |
| SCHEMBL13309568 | 0.74 | MAPK9 (0.60) | KDRMAPK9MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL11091622 | 0.74 | KDR (0.51) | KDRMAPK9MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL15987568 | 0.73 | MAPK9 (0.48) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL28354286 | 0.72 | NPC1 (0.45) | KDRMAPK9MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL1052342 | 0.72 | EGFR (0.45) | KDRMAPK9MAPK10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011022-A | 4-aminocarbazole compound and use of same | TOSOH CORP | 2014-08-27 | — | — | CN | disclosed |