Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.76 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12955359 | 0.87 | AR (1.00) | ARENPP1LMNAHTTNPSR1 | |
| SCHEMBL27970389 | 0.85 | AR (0.57) | ARENPP1LMNAHTTNPSR1 | |
| SCHEMBL19748393 | 0.83 | AR (0.68) | ARENPP1LMNAHTTNPSR1 | |
| SCHEMBL29655150 | 0.83 | AR (0.68) | ARENPP1LMNAHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL31384203 | 0.82 | ENPP1 (0.69) | ARENPP1LMNAHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL28917483 | 0.81 | ENPP1 (0.68) | ARENPP1LMNAHTTNPSR1 | |
| SCHEMBL7122967 | 0.81 | AR (0.77) | ARENPP1LMNAPARP1PRMT5 | |
| SCHEMBL24000756 | 0.81 | ENPP1 (1.00) | ARENPP1LMNAHTTNPSR1 | |
| SCHEMBL12955362 | 0.80 | PARP1 (0.70) | ARENPP1LMNAPARP1 | |
| SCHEMBL19747503 | 0.80 | AR (0.71) | ARENPP1LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003940-A | 2,4-difluoro-5-( phthalazone-1-methyl)-benzoyl piperazine compound and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-08-27 | — | — | CN | claimed |
| CN-104003940-A | 2,4-difluoro-5-( phthalazone-1-methyl)-benzoyl piperazine compound and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-08-27 | — | — | CN | disclosed |