Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279750 | 0.90 | HDAC8 (0.64) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL27976945 | 0.88 | HTR2A (0.55) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL3861303 | 0.85 | HDAC6 (0.56) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL6086626 | 0.83 | HDAC8 (0.55) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL1571627 | 0.82 | MAPT (0.52) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL15712272 | 0.82 | HDAC8 (0.60) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL4941436 | 0.82 | HDAC8 (0.56) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL3861264 | 0.81 | APP (0.53) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL4024181 | 0.81 | CCR9 (0.52) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL6087656 | 0.81 | HDAC8 (0.57) | HDAC6HDAC8HDAC11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104130175-A | Different-position substituted indolone derivatives and application thereof | UNIV TIANJIN SCIENCE & TECH | 2014-11-05 | — | — | CN | disclosed |