SCHEMBL28814

SCHEMBL28814

CCCCCC(N)OP(=O)(O)O

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.63
LAP3 P28838 2/20 0.57
S1PR2 O95136 5/20 0.55
S1PR1 P21453 5/20 0.55
S1PR3 Q99500 5/20 0.55
S1PR4 O95977 4/20 0.55
FDPS P14324 4/20 0.50
PTPN1 P18031 1/20 0.50
LPAR1 Q92633 2/20 0.44
LPAR3 Q9UBY5 2/20 0.44
LPAR2 Q9HBW0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304503 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL4529802 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL28902981 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL28679257 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL8377533 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL29037382 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL2745581 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL7124914 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL28882634 0.98 SMPD1 (0.67) SMPD1LAP3S1PR2S1PR1S1PR3
SCHEMBL27862599 0.96 SMPD1 (0.65) SMPD1LAP3S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2988 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043082-A2 COMPOSITIONS AND METHODS TO IMPROVE RNA PROPERTIES USING BASE, PHOSPHODIESTER LINKAGE, SUGAR BACKBONE, AND CAP MODIFICATIONS THE BROAD INSTITUTE, INC. (US) 2025-02-27 WO claimed
US-20180179541-A1 Modified L-Nucleic Acid NOXXON PHARMA AG (DE) 2018-06-28 US claimed
US-20160376594-A1 Modified L-Nucleic Acid NOXXON PHARMA AG (DE) 2016-12-29 US claimed
US-9328347-B2 siRNA useful in the treatment of flavivirus infection OREGON HEALTH & SCIENCE UNIVERSITY (US) 2016-05-03 US claimed
CN-104593122-A Hydrodynamic drive oil composition for forklift with long service life JIANGSU LOPAL TECH CO LTD 2015-05-06 CN claimed
US-20150038562-A1 Modified L-nucleic Acid NOXXON PHARMA AG (DE) 2015-02-05 US claimed
US-8846631-B2 MicroRNA compositions and methods Regulus Therapeutics Inc. (US) 2014-09-30 US claimed
US-20140287023-A1 5'-TRIPHOSPHATE OLIGORIBONUCLEOTIDES UNIV MCGILL (CA) 2014-09-25 US claimed
US-20140248336-A1 SIRNA USEFUL IN THE TREATMENT OF FLAVIVIRUS INFECTION OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-09-04 US claimed
WO-2014124433-A1 5'-TRIPHOSPHATE OLIGORIBONUCLEOTIDES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-08-14 WO claimed
EP-1071753-A2 NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2001-01-31 EP claimed
WO-2000017346-A2 HAIRPIN HYBRIDIZER MOLECULES FOR MODULATION OF GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2000-03-30 WO claimed
WO-2000004141-A2 USE OF NUCLEIC ACID MOLECULES AS ANTIVIRAL AGENTS RIBOZYME PHARMACEUTICALS, INC. (US) 2000-01-27 WO claimed
US-5998203-A PARTICULARLY USEFUL FOR ENZYMATIC CLEAVAGE OF RNA OR SINGLE-STRANDED DNA. RIBOZYME PHARMACEUTICALS, INC. (US) 1999-12-07 US claimed
WO-1999054459-A2 NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 1999-10-28 WO claimed
EP-0886641-A2 SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES RIBOZYME PHARMACEUTICALS, INC. (US) 1998-12-30 EP claimed
WO-1997026270-A2 SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES RIBOZYME PHARMACEUTICALS, INC. (US) 1997-07-24 WO claimed
US-5633111-A Photoresist composition and article containing 1,2-quinonediazide and an organic phosphorous acid compound FUJI PHOTO FILM CO., LTD. (JP) 1997-05-27 US claimed
US-5254430-A Lithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1993-10-19 US claimed
US-5230988-A Image exposure of plates of aluminum with phosphate or phosphonate compounds and basic compounds FUJI PHOTO FILM CO., LTD. (JP) 1993-07-27 US claimed