Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.61 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | LYN | P07948 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | TEC | P42680 | 2/20 | 0.51 |
| ▸ | TXK | P42681 | 2/20 | 0.51 |
| ▸ | BMX | P51813 | 2/20 | 0.51 |
| ▸ | ITK | Q08881 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839556 | 0.93 | BTK (0.63) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982235 | 0.91 | BTK (0.62) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982739 | 0.89 | BTK (0.64) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982585 | 0.89 | BTK (0.69) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982240 | 0.89 | BTK (0.67) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982576 | 0.88 | BTK (0.66) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982612 | 0.88 | BTK (0.68) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982099 | 0.88 | BTK (0.58) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982110 | 0.87 | BTK (0.61) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982211 | 0.87 | BTK (0.64) | BTKJAK2LCKLYNKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102325753-B | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-10 | — | — | CN | claimed |