Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | DHODH | Q02127 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190936 | 0.90 | NPSR1 (0.81) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL10863692 | 0.88 | DHODH (0.90) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL5174507 | 0.85 | NPSR1 (0.72) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL5174510 | 0.85 | NPSR1 (0.72) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL25188950 | 0.84 | NPSR1 (0.72) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL4742564 | 0.84 | NPSR1 (0.72) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL846104 | 0.84 | DHODH (0.77) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL5046712 | 0.83 | DHODH (1.00) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL25494544 | 0.83 | NPSR1 (0.70) | NPSR1DHODHKDM4EMAPK1LMNA | |
| SCHEMBL25184818 | 0.82 | DHODH (0.79) | NPSR1DHODHKDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751858-B | Quinolinyl-containing tranexamic acid derivative and preparation and application thereof | 沈阳药科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-114751858-A | Quinolinyl-containing tranexamic acid derivative, preparation and application thereof | 沈阳药科大学 | 2022-07-15 | — | — | CN | disclosed |