Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TPH1 | P17752 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233714 | 0.89 | HTT (0.71) | HTTKMT2ATRPM8NPC1RAB9A | |
| SCHEMBL3230760 | 0.86 | HTT (0.68) | HTTKMT2ATRPM8NPC1RAB9A | |
| SCHEMBL3335119 | 0.86 | HTT (0.72) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8593668 | 0.86 | HTT (0.68) | HTTKMT2APOLBNPC1SMN1; SMN2 | |
| SCHEMBL28816317 | 0.86 | HTT (0.68) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2554648 | 0.86 | HTT (0.67) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28816242 | 0.85 | KMT2A (0.53) | HTTKMT2APOLBNPC1RAB9A | |
| SCHEMBL28816269 | 0.85 | HTT (0.64) | HTTKMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4528391 | 0.84 | HTT (0.66) | HTTKMT2APOLBNPC1RAB9A | |
| SCHEMBL22619755 | 0.84 | HTT (0.66) | HTTTRPM8NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933573-A | 3-substituted-1, 2, 4-oxadiazole-5-carboxylic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-08-23 | — | — | CN | claimed |
| CN-114933573-B | 3-substituted-1, 2, 4-oxadiazole-5-carboxylic acid derivative, and preparation method and application thereof | 贵州大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-114933573-A | 3-substituted-1, 2, 4-oxadiazole-5-carboxylic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-08-23 | — | — | CN | disclosed |