Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.71 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.71 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825369 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4818718 | 0.83 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4818722 | 0.83 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4816289 | 0.83 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4816284 | 0.83 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13986023 | 0.83 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13984813 | 0.83 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4824892 | 0.80 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8526041 | 0.80 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8526044 | 0.80 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744263-A | Novel method for efficiently synthesizing 6-hydroxy-2,3-dimethoxy-9-phenanthrenecarboxylic acid methyl ester | UNIV NANKAI | 2015-07-01 | — | — | CN | claimed |