Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817242 | 0.76 | PARP15 (0.50) | NQO2KDM4ELMNAHSD17B10PARP15 | |
| SCHEMBL2554575 | 0.76 | NEK1 (0.49) | PARP15PARP14PARP10TNKS2PARP2 | |
| Hydrochloric Acid SCHEMBL15092584 | 0.75 | NEK1 (0.48) | PARP15PARP14PARP10TNKS2PARP2 | |
| SCHEMBL27370182 | 0.74 | PARP1 (0.48) | NQO2KDM4ELMNAHSD17B10TNKS | |
| SCHEMBL29784738 | 0.73 | NEK1 (0.41) | NEK1 | |
| SCHEMBL28817174 | 0.73 | NEK1 (0.41) | NEK1 | |
| Hydrochloric Acid SCHEMBL15092502 | 0.73 | NEK1 (0.44) | NQO2KDM4ELMNAHSD17B10PARP15 | |
| SCHEMBL28817132 | 0.72 | NQO2 (0.47) | NQO2KDM4ELMNAHSD17B10DYRK1A | |
| SCHEMBL15092574 | 0.72 | NEK1 (0.47) | NQO2KDM4ELMNAHSD17B10PARP15 | |
| SCHEMBL27368941 | 0.71 | PARP1 (0.48) | NQO2KDM4ELMNAHSD17B10TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |