Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 19/20 | 0.56 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.56 |
| ▸ | CDK2 | P24941 | 15/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.56 |
| ▸ | CDK9 | P50750 | 13/20 | 0.56 |
| ▸ | CDK7 | P50613 | 10/20 | 0.54 |
| ▸ | CCNH | P51946 | 10/20 | 0.54 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817295 | 1.00 | CCNK (0.56) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL28817255 | 0.88 | CCNK (0.69) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL28817264 | 0.88 | CCNK (0.69) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL29498422 | 0.87 | CCNK (0.54) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL29498447 | 0.87 | CCNK (0.58) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL24588150 | 0.86 | CCNK (0.55) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL26627138 | 0.85 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL26627145 | 0.85 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL25267815 | 0.84 | CCNK (0.73) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL28817285 | 0.84 | CCNK (0.66) | CCNKCDK12CDK2CCNE1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907407-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 江苏先声药业有限公司 | 2022-08-16 | — | — | CN | disclosed |