Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | PKM | P14618 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817433 | 0.93 | MAPT (0.68) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL29842480 | 0.92 | MAPT (0.67) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL28817442 | 0.91 | MAPT (0.65) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL28817425 | 0.91 | MAPT (0.65) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL28817423 | 0.91 | MAPT (0.65) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL29130781 | 0.84 | MAPT (0.66) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL1958428 | 0.83 | MAPT (0.71) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL21542217 | 0.81 | MAPT (0.73) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL30349527 | 0.81 | MAPT (0.73) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL28817457 | 0.81 | MAPT (0.65) | MAPTPKMPOLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794358-B | Substituted benzenesulfonyl compounds and application thereof in preparing medicines | 中国人民解放军第二军医大学 | 2022-08-12 | — | — | CN | claimed |
| CN-108794358-B | Substituted benzenesulfonyl compounds and application thereof in preparing medicines | 中国人民解放军第二军医大学 | 2022-08-12 | — | — | CN | disclosed |