Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.63 |
| ▸ | TXN | P10599 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743923 | 0.87 | PNP (0.59) | PNPTXNKDM4EMEN1ALDH1A1 | |
| 8-Aminoguanine SCHEMBL21761 | 0.79 | PNP (1.00) | PNPKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL5495950 | 0.76 | PNP (0.50) | PNPTXNKDM4EMEN1ALDH1A1 | |
| SCHEMBL1443897 | 0.72 | PNP (0.58) | PNPTXNKDM4EMEN1ALDH1A1 | |
| SCHEMBL26155923 | 0.71 | PNP (0.73) | PNPKDM4EMEN1ALDH1A1MAPT | |
| 8-Aminoguanine SCHEMBL5513824 | 0.69 | PNP (0.77) | PNPKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL18186143 | 0.68 | PNP (0.51) | PNPTXNKDM4EMEN1ALDH1A1 | |
| SCHEMBL1337886 | 0.68 | PNP (0.42) | PNPTXNMAPTHSD17B10 | |
| SCHEMBL28004912 | 0.68 | PNP (0.42) | PNPTXN | |
| SCHEMBL10629399 | 0.68 | PNP (0.68) | PNPKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | disclosed |