SCHEMBL28817860

SCHEMBL28817860

CCCCC(Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.54
PTGES O14684 5/20 0.54
ALOX5 P09917 5/20 0.54
PPARA Q07869 2/20 0.54
FOLH1 Q04609 2/20 0.51
PPARD Q03181 1/20 0.51
CA2 P00918 1/20 0.50
MAPK1 P28482 1/20 0.50
MMP2 P08253 2/20 0.49
MMP3 P08254 2/20 0.49
CPA3 P15088 1/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29865172 0.90 PPARA (0.56) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL12493539 0.87 PPARA (0.54) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL12493992 0.87 PPARA (0.54) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL12493679 0.86 CYP1A2 (0.55) PPARGPPARAFOLH1CPA3CYP1A2
SCHEMBL604071 0.85 FOLH1 (0.53) PPARGPTGESALOX5PPARAFOLH1
P-Xylene SCHEMBL756336 0.85 PPARG (0.55) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL9188537 0.85 PPARG (0.55) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL7300579 0.85 FOLH1 (0.70) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL9658104 0.84 FOLH1 (0.51) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL27513375 0.83 FOLH1 (0.68) PPARGPTGESALOX5PPARAFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592006-B A kind of synthetic method of phenylpropionic acid compound 郑州大学 2016-10-26 CN disclosed
CN-104592006-A Synthesis method of phenylpropionic acid compound UNIV ZHENGZHOU 2015-05-06 CN disclosed