Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
| ▸ | TYMS | P04818 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068195 | 0.84 | KDM4E (0.60) | DPP4GRM4GRM1TYMS | |
| SCHEMBL18263916 | 0.80 | GRM4 (0.55) | DPP4GRM4TYMS | |
| SCHEMBL28663483 | 0.78 | POLB (0.59) | — | |
| SCHEMBL29714525 | 0.78 | POLB (0.59) | — | |
| SCHEMBL16862998 | 0.75 | HTT (0.67) | DPP4TYMSADORA2A | |
| SCHEMBL23752314 | 0.75 | TYMS (0.55) | DPP4GRM4GRM1TYMSADORA2A | |
| SCHEMBL14029131 | 0.75 | ADORA2A (0.79) | DPP4GRM4GRM1TYMSADORA2A | |
| SCHEMBL18121469 | 0.72 | POLB (0.57) | — | |
| SCHEMBL11018633 | 0.72 | DPP4 (0.70) | DPP4TYMSADORA2A | |
| SCHEMBL11016604 | 0.71 | DPP4 (0.71) | DPP4TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890953-A | Preparation method of 2-aminomethyl pyrimidine hydrochloride | 济南宣正药业有限公司 | 2022-08-12 | — | — | CN | disclosed |