SCHEMBL28818236

SCHEMBL28818236

Cc1cc(OCCCS(C)(=O)=O)nc(C)c1-c1cccc(CCBr)c1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9964504 0.92 FFAR1 (0.48) FFAR1
SCHEMBL9964502 0.87 FFAR1 (0.50) FFAR1
SCHEMBL13564151 0.87 FFAR1 (0.48) FFAR1
SCHEMBL9934971 0.87 FFAR1 (0.46) FFAR1
SCHEMBL27962432 0.84 FFAR1 (0.63) FFAR1
SCHEMBL18963606 0.82 FFAR1 (0.55) FFAR1
SCHEMBL28818237 0.81 FFAR1 (0.42) FFAR1
SCHEMBL27962421 0.78 FFAR1 (0.44) FFAR1
SCHEMBL9934932 0.76 FFAR1 (0.58) FFAR1
SCHEMBL13506915 0.76 FFAR1 (0.62) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710381-A Novel 3-hydroxy-5-arylisothiazole derivative MOCHIDA PHARM CO LTD 2015-06-17 CN disclosed
CN-102712610-B Novel 3-hydroxy-5-arylisothiazole derivatives MOCHIDA PHARM CO LTD 2015-03-04 CN disclosed